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The output amplitude of the differential circuit is studied for differential discrimination in pulsed laser time-of-flight systems. Based on the studies of the probability of detection and the probability of false alarms, the minimum detectable input signal of differential discrimination can be calculated. The results indicate that the differential discrimination detectability of the small signal will be reduced. A combined discrimination is proposed in this Letter to improve the time resolution of the large signal and ensure the probability of detection of the small signal at the same time. A proper value of the circuit parameter is found to balance the time resolutions of the small and large signals.