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目的:研究75例龋齿儿童口腔内幽门螺杆菌(Hp)感染情况,探讨儿童龋齿发病原因。方法:研究对象以2011年7月~2013年12月在我院口腔科就诊的75例龋齿儿童为龋齿组,和其他口腔疾病儿童58例为对照组,用快速尿素酶试剂盒检测所有研究对象口腔内Hp感染情况。结果:龋齿组Hp阳性55例(73.3%)、阴性20例(26.7%),对照组分别为30例(51.7%)、28例(48.3%),龋齿组Hp阳性率明显高于照组(P<0.05);龋齿组轻度、中度、重度儿童Hp阳性率分别51.2%、81.8%、83.3%,重度龋齿儿童Hp阳性性率显著高于轻度及中度儿童,(P<0.05)。结论:龋齿儿童口腔Hp阳性率显著升高,Hp为儿童龋齿的重要致病因素。
Objective: To study the oral cavity Helicobacter pylori (Hp) infection in 75 cases of children with dental caries to explore the causes of children’s dental caries. Methods: From July 2011 to December 2013, 75 children with dental caries treated in our department were selected as caries decoction group and 58 children with other oral diseases as control group. All subjects were tested by rapid urease kit Hp infection in the mouth. Results: The positive rate of Hp in dental caries group was significantly higher than that in the control group (55 cases (73.3%), negative in 20 cases (26.7%), control group (30 cases) P <0.05). The positive rate of Hp in children with mild, moderate and severe caries was 51.2%, 81.8% and 83.3% respectively, and the positive rate of Hp in children with severe caries was significantly higher than that in mild and moderate children (P <0.05) . Conclusion: The positive rate of oral Hp in children with dental caries increased significantly, Hp is an important causative factor in children with dental caries.