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膜性增殖性肾炎(MPGN)是一种免疫复合物性肾炎,治疗困难。作者对1例表现为肾病综合征及肾功能不全的MPGN使用γ球蛋白、尿激酶、肾上腺皮质激素和抗血小板药物治疗,结果肾功能不全改善,蛋白尿减轻。患者男性,28岁,1978年10月体检发现蛋白尿。1980年9月出现颜面及下肢浮肿,诊断肾病综合征,经强的松龙30mg/d隔日治疗好转。1983年3月出现视力模糊;血压增高至220/130mmHg,眼底出血,
Membranous proliferative glomerulonephritis (MPGN) is an immunocomplex nephritis that is difficult to treat. The authors treated 1 patient with MPGN manifesting nephrotic syndrome and renal insufficiency using gamma globulin, urokinase, adrenocortical hormone and antiplatelet drugs, resulting in improved renal insufficiency and reduced proteinuria. Male patient, 28 years old, physical examination found proteinuria in October 1978. September 1980 appeared facial and lower extremity edema, diagnosis of nephrotic syndrome, prednisolone 30mg / d improved every other day. March 1983 blurred vision; blood pressure increased to 220 / 130mmHg, retinal hemorrhage,