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背景:克-雅病(CJD)是一种传染性海绵状脑病。其遗传和医源性形式已被认识,但大多是散发的和不明原因的。作者研究了有关CJD的危险因素,以作为1993-1995年间在欧洲进行的欧洲联盟合作的CJD研究的组成部分。 方法:参与作者研究的405位确诊或可能的CJD患者,参加了1993至1995年间在比利时、法国、德国、意大利、荷兰及英国的根据人群所做的研究。有关这些患者假定的危险因素的资料与405名对照者的数据相比较。
Background: Creutzfeldt-Jakob disease (CJD) is a transmissible spongiform encephalopathy. Its genetic and iatrogenic forms have been recognized, but mostly sporadic and unexplained. The authors studied the risk factors for CJD as part of a CJD study of European Union cooperation in Europe during 1993-1995. METHODS: The 405 confirmed or probable CJD patients participating in the study participated in a population-based study in Belgium, France, Germany, Italy, the Netherlands and the United Kingdom between 1993 and 1995. Data on these hypothesized risk factors were compared with data from 405 control subjects.