低分子量的有机胶凝剂组装形成的有机凝胶可应用于药物缓释体系.本研究中,使用亲水的钙黄绿素和疏水的布洛芬为模型分子,研究其在谷氨酸衍生物有机凝胶体系中的缓释行为.研究表明,与药物分子与有机胶凝剂简单混合的体系相比,亲水或疏水的药物分子在有机凝胶体系中的释放速度显著减缓.SEM的研究发现药物粒子嵌入在有机凝胶的三维网络中,因此,有机凝胶的三维网络结构可认为是实现药物缓慢释放的基质,药物分子从网络中的释放受限导致了其从有机凝胶中的缓释行为. The low molecular weight organic gelling agent assembled organogels can be applied to the drug delivery system.In this study, the use of hydrophilic calcein and hydrophobic ibuprofen as model molecules to study the glutamate derivatives in organic Gel system.The results show that compared with the simple mixing system of drug molecules and organic gelling agent, the release rate of hydrophilic or hydrophobic drug molecules in organogels system is significantly slowed down.SEM study found that Therefore, the three-dimensional network structure of the organic gel can be regarded as the substrate for the slow release of the drug. The limited release of the drug molecule from the network leads to its slow release from the organic gel Release behavior.