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目的检测肺癌及肺部良性疾病患者血清CEA、CA125、CYFRA21的水平,探讨其在肺癌诊断及鉴别的价值。方法采用化学发光法检测80例肺癌和50例良性肺部患者血清CEA、CA125、CY-FRA21的水平。结果肺癌组CEA、CA125、CYFRA21测定值明显高于肺部良性组,3项联合检测的敏感性和特异性分别明显优于单项检测。结论血清CEA、CAl25、CYFRA21联合检测对肺癌诊断有较高的临床参考价值。
Objective To detect the serum levels of CEA, CA125 and CYFRA21 in patients with lung cancer and benign lung diseases, and to explore its value in the diagnosis and differential diagnosis of lung cancer. Methods The levels of serum CEA, CA125 and CY-FRA21 in 80 patients with lung cancer and 50 patients with benign lung were detected by chemiluminescence method. Results The measured values of CEA, CA125 and CYFRA21 in lung cancer group were significantly higher than those in benign lung group. The sensitivities and specificities of the three combined tests were significantly better than those of single test group. Conclusion Serum CEA, CA125, CYFRA21 combined detection of lung cancer diagnosis has a higher clinical reference value.