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目的 探讨放射治疗对鼻咽癌 (NPC)患者听功能的影响。方法 对 3 8例鼻咽癌患者放疗前和放疗后半年、 1年和 3年行听诱发电位、鼓室导抗图和纯音听阈检查。正常对照组为 3 0例健康者。结果 与放疗前比较 ,患者组放疗后半年听功能减退明显 ,以中度以上听力损伤的例数与对照组相比 ,P <0 0 5 ;1～ 3年听觉稍有改善 ,但未能达到放疗前水平 ;此后 ,再次出现听功能减退现象。结论 放疗可影响鼻咽癌患者的听功能 ,放疗后患者的听功能呈起伏式、不可逆的损害。
Objective To investigate the effects of radiotherapy on hearing function in patients with nasopharyngeal carcinoma (NPC). Methods 38 patients with nasopharyngeal carcinoma before radiotherapy and radiotherapy after six months, 1 year and 3 years were measured evoked potential, tympanogram and pure tone hearing threshold examination. Normal control group of 30 healthy people. Results Compared with those before radiotherapy, the hearing loss of patients in the first six months after radiotherapy was significantly lower than that of the control group (P <0.05). The hearing loss was slightly improved in 1 to 3 years but failed to reach Pre-radiotherapy levels; since then, hearing loss again. Conclusion Radiotherapy can affect the hearing function of patients with nasopharyngeal carcinoma, and the hearing function of patients with nasopharyngeal carcinoma is undulating and irreversible damage.