Objective: To observe the effects of leptin on glucose oxidation and glueokinase gene expression in rat liver cells. Methods: Rat liver cells were incubated with leptin of different doses (ranging from 10μg/L to 200μg/L). Control liver cells were Objective: To observe the effects of leptin on glucose oxidation and glueokinase gene expression in rat liver cells. Methods: Rat liver cells were incubated with leptin of different doses ranging from 10 μg / L to 200 μg /