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目的探讨抗精子抗体(antisperm antibody,AsAb)、抗子宫内膜抗体(antiendometrial antibody,EmAb)和抗心磷脂抗体(anticardiolipin antibody,AcAb)在女性不孕中的作用。方法采用ELISA方法检测435例女性不孕患者血清AsAb,EmAb和AcAb。结果 AsAb阳性48例(11.03%),EmAb阳性61例(14.02%),AcAb阳性40例(9.20%);AsAb+EmAb阳性21例(4.83%),AsAb+AcAb阳性11例(2.53%),EmAb+AcAb阳性9例(2.07%),未发现3种抗体同时阳性患者。结论 AsAb,EmAb和AcAb是引起女性不孕的重要免疫学因素,应作为不孕女性常规检查项目。
Objective To investigate the role of antisperm antibody (AsAb), anti-endometrial antibody (EmAb) and anticardiolipin antibody (AcAb) in female infertility. Methods Serum AsAb, EmAb and AcAb were detected in 435 female infertile patients by ELISA. Results AsAb positive in 48 cases (11.03%), EmAb positive in 61 cases (14.02%) and AcAb positive in 40 cases (9.20%), AsAb + EmAb positive in 21 cases (4.83%), AsAb + AcAb positive in 11 cases (2.53% Nine patients (2.07%) were positive for EmAb + AcAb. Three patients with positive antibodies were not found. Conclusions AsAb, EmAb and AcAb are important immunological factors that cause infertility in women and should be used as routine examination items for infertile women.