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单纯疱疹病毒(HSV)是一种常见的人类携带的病原体,人是其唯一的自然宿主。传播方式主要是直接接触传染,亦可通过被唾液污染的餐具而间接传染。目前临床上主要使用的抗HSV化学类药物大都因为作用靶点单一等原因产生了很多HSV的耐药株。相对地,中药因为具有多作用靶点等特点而不易产生耐药性,因此中药抗HSV的研究就显得极为重要。
Herpes simplex virus (HSV) is a common human-borne pathogen, and humans are its only natural hosts. The main mode of transmission is direct contact with infection, but also indirect infection through saliva contaminated tableware. At present, most of the major clinical anti-HSV chemotherapeutic drugs produce a lot of HSV resistant strains because of the single target of action. Relatively, traditional Chinese medicine because of its multiple targets and other characteristics of the resistance is not easy to produce, so the study of anti-HSV Chinese medicine has become extremely important.