长春花碱（VLB）是一种周期特异性抗肿瘤药物，在组织培养中抑制纺锤体的形成而使有丝分裂停止于中期，亦可抑制RNA和脂质的合成。对多种肿瘤治疗效果较好，常与其它药物联合用于治疗多种恶性肿瘤，如：恶性淋巴瘤、绒癌、肺癌、乳腺癌、卵巢癌、皮肤癌等。本文对我科以VLB为主 Vinblastine (VLB) is a cycle-specific anti-tumor drug that inhibits the formation of spindles in tissue culture and arrests mitosis in the mid-stage. It also inhibits the synthesis of RNA and lipids. For a variety of tumors better treatment, often used in combination with other drugs for the treatment of a variety of malignant tumors, such as: malignant lymphoma, choriocarcinoma, lung cancer, breast cancer, ovarian cancer, skin cancer. This article focuses on VLB in our department