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晚近,Moster 报告糖尿病性视网膜病变的发生与内源性胰岛素分泌量有关,这些患者血中 C 肽免疫反应性(CPR,C-peptide immunoreactivity)呈低值。本研究观察糖尿病性微血管与大血管病变与胰岛残存β细胞功能之间的关系。研究对象为以拧制血糖为主要目的,肥胖度在120％以下的糖尿病患者188例。男127例,女61例,年龄18～80岁。血清肌酐值>2.4mg/dl 的中度以上肾损害者不列入研究。42例单纯接受饮食疗法,55例接受口服降糖药,91例应用胰岛素治疗。在入院3天血糖稳定后,连续3天测尿 C 肽,方法为 RIA 法,
Recently, Moster reported that the incidence of diabetic retinopathy is related to the amount of endogenous insulin secretion, and these patients have low C-peptide immunoreactivity (CPR). This study observed the relationship between diabetic microvascular and macrovascular disease and pancreatic β-cell function. The study aimed to twist blood sugar as the main purpose, obesity in 120% of the 188 patients with diabetes. 127 males and 61 females, aged 18 to 80 years. Serum creatinine values> 2.4mg / dl moderate or more renal damage were not included in the study. Forty-two patients received diet alone, 55 received oral hypoglycemic agents and 91 received insulin therapy. 3 days after admission blood glucose was stable, urine C peptide for 3 days, the method for the RIA method,