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为了了解宫颈癌病人阴道表层细胞核固缩指数(Karyopyknotic Index,KPI)和血雌二醇水平的关系,以及KPI数值和肿瘤消长的关系,作者选绝经5年以上妇女38人,分成3组。第一组(对照组)11例,平均年龄58岁,无任何肿瘤症状和激素紊乱迹象。第二组11例子宫颈癌病人(根据UICC为Ⅰ-Ⅲ期),平均年龄60岁。第三组16例,平均年龄64岁,为已接受过放疗并为治疗后两年或两年以上无任何复发症状的子宫颈癌病人(根据UICC为Ⅰ-Ⅲ期)。所有病例细胞学标本取自阴道后壁,同时测血雌二醇。第二组癌症病人细胞学标本和血分别在放疗前和放疗后6周采取。阴道涂片用巴氏染色。KPI数值由计数300~400个表层鳞状
In order to understand the relationship between Karyopyknotic index (KPI) and blood estradiol level in patients with cervical cancer and the relationship between KPI value and tumor growth and decline, we selected 38 women over 5 years of menopause and were divided into 3 groups. The first group (control group) 11 cases, mean age 58 years old, without any signs of cancer and hormone disorders. The second group of 11 patients with cervical cancer (according to UICC for stage Ⅰ-Ⅲ), with an average age of 60 years. The third group of 16 patients with an average age of 64 years were patients with cervical cancer (stage I-III according to UICC) who had received radiotherapy and had no recurrence after two or more years of treatment. All cases of cytological specimens taken from the vaginal wall, while measuring blood estradiol. The second group of cancer patients cytology specimens and blood were taken before radiotherapy and 6 weeks after radiotherapy. Vaginal smears were stained with Pap. KPI values from the count of 300 to 400 surface squamous