自从Young(1971)发现了猴眼视网膜光受体细胞外节持续不断的更新和色素上皮负责除去杆体细胞外节末端盘膜的事实以来,对于某些视网膜疾病的性质出现了新的概念。最近研究发现猴眼视网膜杆体细胞每天产生80～90个盘膜,整个外节盘膜由产生到脱落需9～13天,每个色素上皮细胞每天吞噬和歼灭约3000个盘膜。视网膜生物学给予我们令人鼓午的新前景。为了供人一生70年或更多年代中每天消化大量的外来性物质,色素上皮细胞必须具有高度发育的吞噬溶酶体系统。色素上皮并不像网状内皮系统的吞噬细胞那样,它只有低度的有丝分裂,终身是留在原位置不动。这种事实的生物学含意是:色素上皮细胞过度吞噬的或无能力消化的东 Ever since Young (1971) found continuous renewal of the extracellular portion of the monkey retina photoreceptor and the fact that the pigmented epithelium is responsible for removing the terminal panicle of the rod, a new concept has emerged for the properties of certain retinal diseases. Recent studies have found that monkey eye retinal rod cells produce 80 to 90 discs a day, the entire outer disk to produce from shedding to 9 to 13 days, each pigment epithelial cells phagocytosis and destroy about 3,000 discs per day. Retinal biology gives us a delightful new perspective. For human life 70 days or more every day to digest a large number of foreign substances, pigment epithelial cells must have a highly developed phagolysosome system. Pigment epithelium is not like the reticuloendothelial system of phagocytes, it has only low mitosis, lifelong stay in the original position does not move. The biological implications of this fact are: overgrowth or incapacitation of pigmented epithelial cells