在过去的 2 0年里出现了许多新的免疫抑制剂 ,然而移植排斥问题并未得到完全解决。对于大多数药物来说 ,需要长期给药。由于这些免疫抑制剂是非特异性的 ,在控制移植物排斥的同时 ,要面临发生致死性感染和肿瘤的危险。此外 ,不管用任何药物且用的如何巧妙 ,对于慢性排斥都无济 Many new immunosuppressants have emerged over the past 20 years, however, the issue of transplant rejection has not been completely resolved. For most drugs, long-term administration is required. Because these immunosuppressive agents are nonspecific, they are at the same time as controlling graft rejection and are at risk for fatal infections and tumors. In addition, no matter how clever and use any drugs, for chronic rejection are not cheap