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加速性排斥反应是肾移植的一种严重排斥反应类型,因其症状重,肾功能损害发生快,逆转困难而成为处理术后早期抗排斥反应的难点。本科自1997年1月～4月应用抗T淋巴细胞球蛋白(ATG)治疗此种反应3例,报告如下。 资料与方法 1.免疫抑制剂的应用 (1)肾移植术后按我科常规给予三联用药:环胞素A(CsA)[5～7mg/(kg·d)]+强的松(30mg/d)+硫唑嘌呤(100mg/d)。术后前3天给予甲基强的松龙(1.0g/d)静点冲击治疗,3天后改口服强的松(30mg/d)。(2)ATG应用:
Acceleration of rejection is a type of severe rejection in renal transplantation. It is a difficult point to deal with the early postoperative anti-rejection because of its severe symptoms, rapid renal dysfunction and difficult reversal. Undergraduate from January 1997 to April application of anti-T lymphocyte globulin (ATG) treatment of such reactions in 3 cases, the report is as follows. Materials and Methods 1. The application of immunosuppressive agents (1) According to our department after routine renal transplantation triple therapy: CsA [5-7mg / (kg · d)] + prednisone (30mg / d) + Azathioprine (100 mg / d). The first 3 days after the administration of methylprednisolone (1.0g / d) static impact treatment, 3 days later oral prednisone (30mg / d). (2) ATG application: