【摘 要】
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INTRODUCTIONGastrin is a trophic gastrointestinal hormone which is secreted by G cell. Gastrin has long been considered a growth stimulatory hormone for mucosa
【机 构】
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Department of General Surgery,Department of Pathology
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INTRODUCTIONGastrin is a trophic gastrointestinal hormone which is secreted by G cell. Gastrin has long been considered a growth stimulatory hormone for mucosa of the gastrointestinal tract[1]. The growth responses of certain colorectal cancer cells, and xenografts, can be stimulated by endogenous gastrin[2]. Protein kinase C (PKC) is a family of isozymes that plays a crucial role in transducing signals of many hormones, growth peptides,neurotransmitters, and its activation is crucial in tumor promotion[3]. PKC is also involved in regulating cellular proliferation[4].
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