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内分泌肿瘤的种类因年龄而分布不同,例如甲状旁腺腺癌和胰岛细胞瘤以较高年龄组为多,60岁以上者分别占27.1%及16.6%。而Cushing氏综合征及原发性醛固酮增多症在青年人较多。作为老年人的特点,有多数脏器损害而常无典型症状,容易误诊,内分泌肿瘤亦不例外。伴随年龄增加,激素的合成、分泌、代谢、作用、调节等机能发生变化,在评价检查结果时常须考虑年龄的差别,另外应尽可能采用非侵袭性检查法。本文就老年人内分泌肿瘤的发生率、病情特点、诊断及治疗问题作一概述。
The types of endocrine tumors vary according to their age. For example, parathyroid adenocarcinoma and islet cell tumor are higher in the higher age group, with those over the age of 60 accounting for 27.1% and 16.6% respectively. The Cushing’s syndrome and primary aldosteronism in young people more. As a feature of the elderly, most of the organ damage and often without typical symptoms, easy to misdiagnosis, endocrine tumors are no exception. With age, hormone synthesis, secretion, metabolism, role, regulation and other functions change in the evaluation of the results often have to consider age differences, the other should be used as far as possible non-invasive test. In this paper, the incidence of endocrine neoplasms in the elderly, the characteristics of the disease, diagnosis and treatment issues are summarized.