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本文就叶下珠注射液的配制方法及其稳定性的影响因素进行了研究探讨。结果表明:杂质沉淀剂、溶液的PH值以及抗氧剂对叶下珠注射液稳定性具有较大的影响,采用壳聚糖澄清剂既能较有效地除去杂质,又不引起有效化学成分丢失,因而能保证叶下珠注射液的化学稳定性。
In this paper, the preparation methods of Ye Xizhu injection and the influencing factors of its stability were studied. The results show that: the impurity precipitation agent, the pH value of the solution and the antioxidant have a great influence on the stability of Ye Xiazhu injection. Using chitosan clarifier can effectively remove impurities without causing loss of effective chemical components. Therefore, it can ensure the chemical stability of Ye Xiazhu injection.