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目的:了解冠心病合并睡眠呼吸暂停综合征患者的发生率,并探讨其临床特点。方法:对2004年11月-2005年2月入住我中心行冠状动脉造影的患者,进行多导睡眠呼吸监测,并对其临床症状进行分析。结果:175例患者接受检查入选,冠状动脉造影确诊冠心病患者135例,其中合并睡眠呼吸暂停综合征62．2％(84／135);非冠心病患者40例,其中合并睡眠呼吸暂停综合征40％(16／40),P<0．005。冠心病合并睡眠呼吸暂停综合征与冠心病不合并睡眠呼吸暂停综合征两组之间嗜睡评分、腰臀比、夜间胸痛或憋醒、夜尿增多、晨起口干有明显差别,P< 0．05。Logistic回归分析显示体重指数、夜尿增多、夜间胸痛或憋醒是冠心病患者合并睡眠呼吸暂停综合征的危险因素。结论:冠心病合并睡眠呼吸暂停综合征发病率高,应对冠心病患者进行睡眠呼吸监测,尤其夜间反复发作胸痛憋气、夜尿增多、肥胖的患者应进行睡眠呼吸监测,尽早进行诊断及治疗。
Objective: To understand the incidence of coronary heart disease complicated with sleep apnea syndrome, and to explore its clinical features. Methods: From November 2004 to February 2005, patients admitted to our center underwent coronary angiography were monitored for polysomnography and their clinical symptoms were analyzed. Results: A total of 175 patients were enrolled in the study. Of the 135 patients diagnosed with coronary artery disease by coronary angiography, 62.2% (84/135) had combined sleep apnea syndrome and 40 patients with non-coronary heart disease, of which, patients with sleep apnea syndrome 40% (16/40), P <0.005. Coronary heart disease with sleep apnea syndrome and coronary heart disease without sleep apnea syndrome between the two groups, sleepiness score, waist-hip ratio, night chest pain or arousal, nocturia, early morning dry mouth were significantly different, P <0 .05. Logistic regression analysis showed that body mass index, nocturia, nighttime chest pain or arousal were risk factors for patients with CHD complicated by sleep apnea syndrome. Conclusion: The incidence of coronary heart disease complicated with sleep apnea syndrome is high. Sleep apnea monitoring should be performed in patients with coronary heart disease, especially in patients with repeated episodes of chest pain, suffocation, nocturia and obesity. Sleep apnea monitoring should be performed as soon as possible for diagnosis and treatment.