五十年代中,应用钯催化剂氧化乙烯制备乙醛的工业方法,称为Wacker 法。在该法问世以前,钯催化剂在有机合成中主要用于部份氢化和氧化。嗣后,对该法的研究,开辟了钯络合物在有机合成研究领域中的应用,激起有机钯化学的热潮。钯催化剂不仅应用于部份氢化和氧化,且陆续应用于烃化、偶合、环合、加成、重排、胺化、氯化、消除和脱保护基等反应。反应 In the fifties, the industrial method of preparing acetaldehyde from ethylene oxide by palladium catalyst was called Wacker method. Before the advent of the law, palladium catalysts were mainly used for partial hydrogenation and oxidation in organic synthesis. Subsequently, the study of this law opened up the application of palladium complexes in the field of organic synthesis and aroused the craze of organic palladium chemistry. Palladium catalysts are not only applied to partial hydrogenation and oxidation, but also applied to reactions such as alkylation, coupling, cyclization, addition, rearrangement, amination, chlorination, elimination and deprotection. reaction