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目的:评价三七粉与氢氧化钙糊剂联合封药作为根管消毒剂预防根尖周炎根管治疗间急症的临床疗效。方法:选择93例诊断为根尖周炎的患者分为2组,进行随机单盲对照研究。实验组(48例)采用三七粉与氢氧化钙糊剂联合作为根管封药;对照组(45例)常规使用氢氧化钙糊剂进行根管封药。比较两组患者封药后48 h的疼痛程度及7 d后复诊时的疗效评价,在6个月后对根管治疗术的临床疗效进行随访与评价。结果:实验组封药48 h后疼痛发生率为20.8%,低于对照组42.2%,两组对比差异具有统计学意义(P<0.05);实验组封药7 d后治疗成功率为91.7%,高于对照组75.6%(P<0.05);根管充填术后6个月,实验组、对照组间患者的治疗有效率分别为93.8%和88.9%,差异无统计学意义(P>0.05)。结论:三七粉与氢氧化钙糊剂联合封药能有效缓解患者根管治疗期间急症疼痛。
Objective: To evaluate the clinical curative effect of Panax ginseng powder combined with calcium hydroxide sealant as root canal disinfectant to prevent acute root canal disease during root canal therapy. Methods: Ninety-three patients diagnosed as periapical periodontitis were divided into two groups and randomized single-blind controlled study. The experimental group (n = 48) was treated with notoginseng powder and calcium hydroxide paste as the root canal sealant. The control group (n = 45) was routinely treated with calcium hydroxide paste for root canal sealant. The pain scores at 48 hours after drug sealant in both groups were compared, and the curative effect was evaluated after 7 days. The clinical curative effect of root canal therapy was followed up and evaluated after 6 months. Results: The incidence of pain in experimental group was 20.8% after 48 h, which was lower than that in control group (42.2%) (P <0.05), and the success rate of treatment in experimental group was 91.7% (P <0.05). After 6 months of root canal filling, the effective rates of treatment group and control group were 93.8% and 88.9%, respectively, with no significant difference (P> 0.05) ). Conclusion: The combined treatment of notoginseng powder and calcium hydroxide paste can effectively relieve the acute pain in patients during root canal therapy.