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目的 本文以探究无创呼吸机对高龄慢性心力衰竭急性失代偿的临床应用效果为目的 ，另配合护理措施，分析其影响价值?方法 以随机抽取法在2019年1月至2020年12月，选择本院36例高龄慢性心力衰竭急性失代偿患者作为此次研究对象，再以自由抽签的形式将其均分为试验组?参照组，试验组予以无创呼吸机治疗方案再配合综合护理措施，参照组则予以基本治疗配合常规护理措施，对两组采取不同治疗并予以配合护理措施，将其治疗效果及对护理工作的满意度进行对比分析，以明确的数据为标准并做总结性报告?结果 治疗后试验组呼吸频率?心率?平“,”Objective This paper aims to explore the clinical application effect of noninvasive ventilator on acute decompensation of advanced chronic HF， and observe it with nursing measures to analyze the impact value. Methods Thirty-six patients with chronic heart failure decompensation were randomly selected from 2019 January to 2020 December， divided into experimental groups in the form of free draw， noninvasive ventilator treatment， basic treatment， and adopted different treatment and the nursing measures， comparing the treatment effect and nursing satisfaction， with clear data as the standard and summary report. Results After treatment， the test group\'s respiratory rate， heart rate， mean arterial pressure， arterial oxygen partial pressure， and left ventricular ejection fraction were better than those before treatment and the reference group， with significant differences (P <0.05). After intervention， the nursing satisfaction and treatment efficiency of the experimental group were significantly higher than those of the reference group， with significant differences (P <0.05). Conclusion Non-invasive ventilator treatment， simple operation method，no traumatic to patients， treating patients with effective nursing measures， its clinical application effect is significant， alleviate the patient\'s heart and lung function， improve the respiratory condition， improve the rehabilitation， at the same time， improve the quality of nursing， also improve the patients\' satisfaction with nursing work， and advocate large-scale promotion and application.