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目的:观察对慢性阻塞性肺疾病急性加重期(AECOPD)合并呼吸衰竭患者使用无创正压双水平通气(BiPAP)治疗的临床效果。方法:选取2013年1月~2014年2月收治AECOPD患者116例,随机分为实验组与对照组,对照组实施常规治疗,实验组在此基础上实施BiPAP通气治疗,对比观察两组患者临床情况结果:实验组患者治疗2d后动脉血气分析指标(PaO2、PaCO2与SO2)明显优于对照组,P<0.05,差异均具有统计学意义。结论:通过BiPAP辅助治疗AECOPD患者,能够有效改善其缺氧状况,快速缓解患者病情,具有显著的临床应用效果与价值。
Objective: To observe the clinical effect of noninvasive positive pressure bi-level ventilation (BiPAP) on patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and respiratory failure. Methods: One hundred and sixty-six patients with AECOPD admitted between January 2013 and February 2014 were randomly divided into experimental group and control group. The control group received routine therapy. On the basis of this study, the experimental group received BiPAP ventilation, and compared the clinical effects of the two groups Results: The arterial blood gas analysis indexes (PaO2, PaCO2 and SO2) in experimental group were significantly better than those in control group 2 days after treatment, P <0.05, the differences were statistically significant. Conclusion: BiPAP adjuvant treatment of patients with AECOPD can effectively improve the hypoxic condition, and quickly alleviate the patient’s condition, with significant clinical effects and values.