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近年来,皮肤病理学领域内有了很多新进展,不仅发现了一些新的疾病或对某些疾病有了新的分类,而且在发病机理方面,由于电镜、免疫电镜、免疫荧光、免疫组化技术以及单克隆抗体的应用,也取得了不少进展。概括起来有下列四个方面:(1)关于皮肤肿瘤组织发生的新概念;(2)郎格罕氏细胞(CC)及其在炎症性与肿瘤发病机理的关系;(3)第一期恶性黑色素瘤(恶黑)的预后;(4)皮肤免疫病理,特别是单克隆抗体的应用,使皮肤病理学出现了新面貌,现将部分内容综述如下(有关新病种详见新版皮肤组织病理学,有关单克隆抗体的应用,见另文)
In recent years, there have been many new advances in the field of dermatology, not only the discovery of new diseases or new classifications of certain diseases, but also in the pathogenesis, due to electron microscopy, immunoelectron microscopy, immunofluorescence, and immunohistochemistry. The application of technology and monoclonal antibodies has also made a lot of progress. To sum up, there are the following four aspects: (1) new concepts on the occurrence of skin tumor tissue; (2) Langerhans cell (CC) and its relationship with inflammatory and tumor pathogenesis; (3) the first phase of malignant The prognosis of melanoma (bad black); (4) Skin immune pathology, especially the application of monoclonal antibodies, has brought new appearance to skin pathology. Now part of the content is summarized as follows (For details of new diseases, see the new skin tissue disease. Science, application of monoclonal antibodies, see separate article)