新生儿硬肿症是新生儿期常见疾病之一,病死率高达40～50%,我科1973年1月～1987年3月共收治60例,占同期住院新生儿的7.96%。今就其治疗及死因作一分析和讨论。一、临床资料60例中男45例,女15例;发病日龄为生后1～11天;冬季发病的53例(88.3%),临床表现皆体温不升(指<35℃)、反应低下、哺乳差、哭声低、局部或全身皮下脂肪集聚部位变硬。多有口周青紫、心率减慢、心音低等。95%有合并症,其中肺炎45例。败血症5例、颅内出血2例、脐炎及皮肤感染5例。病情程度依据1983年临潼会议(《关于新生儿硬肿诊断及防治建议》精神,符合轻度者22例,中度15例,重度23例。二、治疗及转归本文60例皆予复温、合理喂养以及维生素E、肾上腺皮质激素常规治疗,并给 Neonatal scleredema is one of the most common neonatal diseases with a mortality rate of 40-50%. 60 cases were treated in our hospital from January 1973 to March 1987, accounting for 7.96% of the newborns hospitalized in the same period. Now on the treatment and cause of death for an analysis and discussion. First, the clinical data of 60 cases, 45 males and 15 females; onset age of 1 to 11 days after birth; winter onset in 53 cases (88.3%), clinical manifestations are all body temperature does not rise (referring to <35 ℃), the reaction Low, poor breastfeeding, crying low, local or systemic subcutaneous fat accumulation site hardens. There are more blushing, slow heart rate, low heart sound. 95% have complications, including 45 cases of pneumonia. 5 cases of sepsis, 2 cases of intracranial hemorrhage, 5 cases of omphalitis and skin infections. The severity of illness was based on the meeting of Lintong in 1983 (“On the diagnosis and prevention and treatment of neonatal peduncle sclerosis”, in line with the mild in 22 cases, moderate in 15 cases, severe in 23. Second, the treatment and prognosis of 60 cases are rewarmed , Reasonable feeding and vitamin E, adrenal cortex hormone routine treatment, and give