变应原作为持续性哮喘的触发因子不能解释早期(即刻的)过敏性哮喘反应的许多临床特征。但是由于变应原引起的后期哮喘反应和非过敏性支气管反应性增高的特征,可帮助解释持续性过敏性哮喘发病机制中变应原的地位。 变应原引起的早期哮喘反应是由于变应原与特异性抗原—IgE分子相结合固定于肥大细胞,导致肥大细胞脱颗粒而引起。实验证明:吸入抗原后 Allergens, as triggers of persistent asthma, do not account for many of the clinical features of early (immediate) allergic asthma responses. However, due to the characteristics of allergen-induced late asthma response and non-allergic bronchial reactivity, it can help explain the role of allergens in the pathogenesis of persistent allergic asthma. Allergen-induced early asthmatic response is due to allergen-specific antigen-IgE molecules bound to mast cells, leading to degranulation of mast cells caused. Experiments show that: after antigen inhalation