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血管老化是心血管事件发生的主要危险因素之一。近年来随着“膜学说”的发展,大电导钙激活钾通道在血管老化中的改变日益受到关注,其与心血管事件的发生关系密切。本文就钙激活钾通道在血管老化中的改变和意义作一综述。
Vascular aging is one of the major risk factors for cardiovascular events. In recent years, with the development of “membrane theory”, the changes of the large-conductance calcium-activated potassium channels in the aging of blood vessels are receiving more and more attention, which is closely related to the occurrence of cardiovascular events. This review summarizes the changes and significance of calcium-activated potassium channel in vascular aging.