肠易激综合征(IBS)是常见的功能性胃肠病,其发病机制尚未完全阐明,部分IBS患者的治疗效果还不满意。近年研究陆续发现一些与IBS发病有关的病理生理学改变,对IBS是否属于功能性疾病提出强烈质疑。有流行病学调查发现IBS与支气管哮喘的流行病学具有相关性。此文就IBS和支气管哮喘的发病机制中的变态反应、炎症、内脏高反应性等方面的相关性进行探讨,为探索IBS有效治疗方案提供新的思路。 Irritable bowel syndrome (IBS) is a common functional gastrointestinal disease, its pathogenesis has not been fully elucidated, and some IBS patients are not satisfied with the treatment. In recent years, studies have gradually found some pathophysiological changes related to the pathogenesis of IBS and strongly questioned whether IBS belongs to functional diseases. Epidemiological studies have found that IBS and epidemiology of bronchial asthma are relevant. This article discusses the correlation between IBS and the pathogenesis of bronchial asthma such as allergy, inflammation, visceral hyperreactivity and so on, providing new ideas for exploring effective treatment of IBS.