驱虫净又名四咪唑,为一较新合成的广谱驱肠虫药。对蛔虫、蛲虫和钩虫都有作用,尤其用于蛔虫病,疗效较满意,比哌哔嗪的抗蛔虫作用强得多,副作用又少。实验证明,四咪唑能使蛔虫肌肉产生强直性收缩,最后麻痹虫体。其作用是抑制琥珀酸脱氢酶的活性,阻断延胡索酸还原为琥珀酸,影响蛔虫肌肉的无氧代谢。本药毒性低,疗效高,服后个别人仅有轻度头昏、头痛、心悸、出汗、恶心呕吐、腹痛、失眠等。目前对该药的副反应似见增多,且表现不一。已见诸报告者有精神异常、哭叫不安、神经兴奋性增高、甚至引起一时性截瘫等,近又见有过敏合併双目暂时性失明 Insecticide net also known as tetrazolium, a relatively new synthetic broad-spectrum anthelmintics. On roundworms, pinworms and hookworms have a role, especially for ascariasis, the effect is more satisfactory, than piperazine-resistant roundworm is much stronger, fewer side effects. Experiments show that four imidazole can make Ascaris muscle tonic contraction, and finally paralysis worms. Its role is to inhibit succinate dehydrogenase activity, blocking fumarate reduction to succinate, affecting the roundworm muscle anaerobic metabolism. The drug is low toxicity, high efficacy, after serving individual only mild dizziness, headache, palpitations, sweating, nausea, vomiting, abdominal pain, insomnia and so on. The side effects of the drug seems to increase, and the performance varies. Have seen the reports of mental disorders, crying uneasy, increased excitability of the nerves, and even cause temporary paraplegia, etc., recently see the allergy combined binocular temporary blindness