小鼠支气管—肺泡巨噬细胞对皮炎芽生菌的杀真菌活性

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Brass等曾于1982年证明取自以ConA刺激的或免疫小鼠的腹腔巨噬细胞(PM)与有毒酵母型皮炎芽生菌菌株共同培养24小时,并与未受刺激的非免疫小鼠的PM相比较,发现有明显抑制真菌生长的作用。Brummer等于1983年证明腹腔感染BCG或用ConA致敏的小鼠,取其PM作4小时培养的测定试验,可使皮炎芽生菌的菌落形成单位(cfu)减少。肺部感染时,与之相关的支气管-肺 Brass et al. Demonstrated in 1982 that co-cultures of peritoneal macrophages (PMs) from ConA-stimulated or immunized mice with strains of the virulent yeast type dermatitis were co-cultured for 24 hours with PM of unstimulated non-immunized mice In comparison, it was found that there was a significant inhibitory effect on fungal growth. Brummer is equal to 1983 to prove that intraperitoneal infection with BCG or ConA sensitized mice, take the PM for 4 hours culture assay can reduce the colony forming units (cfu) blast dermatitis. Pulmonary infection, associated with bronchial-pulmonary
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