目的分析危重患儿脑脊液(CSF)与动脉血酸碱、气体分析的联系。方法对50例危重患儿同步监测CSF和动脉血酸碱、气体分析。结果CSF与动脉血的酸碱及气体分析中pH、PO2、PCO2、HCO-3、BE差异有显著意义(P<0.01、P<0.05、P<0.01、P<0.01、P<0.01),其中CSFpH、HCO-3、BE均值较血液低,CSFPCO2较动脉血PaCO2高;CSFPCO2与动脉血PCO2有正相关性(r值为0.764,P<0.01),CSFHCO-3与动脉血HCO-3有正相关性(r值为0.788,P<0.01),CSFpH与动脉血pH相关性低(r值为0.49,P<0.01)。结论部分CSF与动脉血酸碱气体分析数据明显相关,临床上可以通过实测动脉血数据推测CSF的相应值。 Objective To analyze the relationship between cerebrospinal fluid (CSF) and arterial acid, alkali and gas analysis in critically ill children. Methods 50 cases of critically ill children were monitored simultaneously CSF and arterial acid, gas analysis. Results The differences of pH, PO2, PCO2, HCO-3 and BE in CSF and arterial blood were significant (P <0.01, P <0.05, P <0.01, P <0.01, P <0.01) CSF, HCO-3, and BE were lower than those in blood. CSFPCO2 was higher than arterial blood PaCO2. CSFPCO2 was positively correlated with arterial PCO2 (r = 0.764, P <0.01) (R = 0.788, P <0.01). The correlation between CSFpH and arterial blood pH was low (r = 0.49, P <0.01). Conclusions Some of the CSFs are significantly related to the data of arterial acid-base gas analysis. The corresponding value of CSF can be inferred from the measured arterial blood data clinically.