毛叶轮环藤[Cyclea barbata(Wall)Miers]为防己科轮环藤属植物,在海南岛有野生。其根俗称“银不换”。主治喉炎、腹痛及牙痛,并用于跌打损伤。中国人民解放军第一八七医院首先发现并经临床试验,证明其总生物碱的碘甲烷盐,具有明显的横纹肌松弛作用。 国外,从该植物中,已分得十二种生物碱。本文报道从“银不换”的总生物碱中,除分得 The hairy looper [Cyclea barbata (Wall) Miers] is a member of the genus Echinochorthoides, which is wild in Hainan Island. Its root is commonly known as “silver does not change.” Indications laryngitis, abdominal pain and toothache, and for bruises. The 187th Hospital of the Chinese People’s Liberation Army first discovered and passed clinical trials to prove that its total alkaloid iodomethane salt has a pronounced striated muscle relaxation effect. Abroad, twelve alkaloids have been assigned to this plant. This article reports that in addition to the total alkaloids in which “silver does not change”