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目的研究复方米非司酮(米非司酮30mg+双炔失碳酯5mg)对终止早期妊娠的疗效与副作用。方法选择因非意愿妊娠要求终止妊娠的孕<49d的妇女159例,随机分为观察组79例,给予复方米非司酮1片,qd×2d;对照组80例,给予米非司酮2片(50mg),bid×3d,均于末次服药后给予米索前列醇促进孕囊排出。结果流产成功率:观察组和对照组分别为97.47%(77/79)和90.25%(72/80);另外,观察组孕囊排出时间、出血量及出血时间均明显小于对照组,二组在副作用方面均无统计学差异。结论复方米非司酮可加快孕囊排出时间,减少出血量,提高流产成功率,同时具有用药简便,用药剂量小的特点。
Objective To study the curative effect and side effects of compound mifepristone (mifepristone 30mg + anordrin 6mg) on termination of early pregnancy. Methods A total of 159 pregnant women who were expecting their pregnancies due to unplanned pregnancy were randomly divided into observation group (n = 79) and mifepristone (qd) for two days. The control group (n = 80) received mifepristone 2 Tablet (50mg), bid × 3d, were given the last dose of misoprostol to promote gestational sac discharge. Results The success rate of abortion was 97.47% (77/79) and 90.25% (72/80) respectively in the observation group and the control group. In addition, the gestational sac discharge time, bleeding volume and bleeding time in the observation group were significantly less than those in the control group, No side effects in statistical differences. Conclusion Compound mifepristone can speed up the discharge of gestational sac, reduce the amount of bleeding, improve the success rate of abortion, and has the characteristics of simple medication and small dosage.