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目的分析六种抗生素使用方案治疗非淋菌性尿道(宫颈)炎的效果及影响因素。方法对2001年1月1日至今我所性病门诊的878份有随访的非淋菌性尿道(宫颈)炎的病历进行回顾性分析。结果六种方案对沙眼衣原体的平均治愈率为57.116%,且不同方案的治愈率有显著性差异;六种方案对解脲支原体的平均治愈率为69.556%,不同方案的治愈率无显著性差异;衣原体和支原体的混合感染显著降低了各自的清除率。结论当前非淋菌性尿道(宫颈)炎的治疗效果并不乐观,耐药株的不断出现值得广泛关注;治疗方案疗效的影响因素及机理有待深入研究。
Objective To analyze the efficacy and influential factors of six antibiotic regimens in the treatment of non-gonococcal urethritis (cervix) inflammation. Methods A retrospective analysis was conducted on the records of 878 non-gonococcal urethritis (cervicitis) patients who visited our STD clinic from January 1, 2001 to the present. Results The average cure rate of Chlamydia trachomatis was 57.116%, and the cure rates of different regimens were significantly different. The average cure rates of six kinds of regimens to Ureaplasma urealyticum were 69.556%, and the cure rates of different regimens were not significantly different The mixed infection of chlamydia and mycoplasma significantly reduced their clearance rate. Conclusions The current non-gonococcal urethritis (cervix) treatment is not optimistic. The emergence of resistant strains deserves extensive attention. The influencing factors and mechanism of therapeutic regimens need further study.