【摘 要】
：
Colloidal mesoporous silica nanoparticles functionalized with carboxy-terminated polyethylene glycol (CMS-PEG-COOH) were successfully synthesized by covalently grafting dicarboxy-terminated polyethylene glycol (HOOC-PEG-COOH) on the surface of the amino f
【机 构】
：
Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei Provincial Cooperative Inn
【出 处】
：
武汉理工大学学报（材料科学版）（英文版）
论文部分内容阅读
Colloidal mesoporous silica nanoparticles functionalized with carboxy-terminated polyethylene glycol (CMS-PEG-COOH) were successfully synthesized by covalently grafting dicarboxy-terminated polyethylene glycol (HOOC-PEG-COOH) on the surface of the amino functionalized CMS nanoparticles with amide bond as a cross linker. Moreover, the structural and particle properties of CMS-PEG-COOH were characterized by nuclear magnetic resonance spectroscopy (1H-NMR), transmission electron microscopy (TEM), dynamic light scattering (DLS), nitrogen adsorption-desorption measurements, X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR). The nanomaterials presented a relatively uniform spherical shape morphology with diameters of about 120 nm ,and favorable dispersibility in weak acid solution. The CMS-PEG-COOH exhibited no changes in the state of amorphous, while the mesopores sizes of 5.25 nm might provide the nanomaterials with large capacity for the loading and releasing of drugs. So the results indicated that CMS-PEG-COOH might be a critical nanomaterial for drug delivery system in the future.
其他文献
Thaumasite form of sulfate attack (TSA) can be observed in cement containing limestone under sulfate condition at low temperature. Mixing with suitable mineral admixture could be a good choice to improve the TSA resistance performance of cement-based mate
To solve the problems of poor forming and easy adhesion of the stainless steel, Cu alloyed layer on the stainless steels was prepared by the double glow plasma surface alloying technique. The experimental results indicated that the supersaturated copper d
The main objective of this paper is to evaluate the effects of asphalt concrete types on the microstructural characteristics at high-temperature.Suspend-dense structure and Skeleton-dense structure were selected to investigate the deformation of pavement
Conductive polymers show great promise because of their electrical property based on bioelectricity in vivo. In order to search electro-activity materials which insure abduction of tissue, we synthesized conductive nerve conduits with poly-dl-lactic-acid
Various lead-free ceramics have been investigated in search for new high-temperature dielectrics. In particular, Bi4Ti3O12 is a type of ferroelectric ceramics, which is supposed to replace lead-containing ceramics for its outstanding dielectric properties