目的探讨急性胰腺炎(AP)早期内镜治疗的临床疗效。方法治疗组(37例)除行常规内科综合治疗外,在AP早期行胰胆管造影检查,并根据其结果当即行乳头括约肌切开术和/或鼻胆管引流术等内镜下治疗。对照组(56例)仅行常规内科综合治疗。结果治疗组腹痛缓解时间及平均住院天数均低于对照组(P<0.05)。治疗组内科治愈率达97.3%(36/37),对照组为78.6%(44/56)。结论AP的早期内镜治疗以微小创伤达到满意的引流效果,对急性胰腺炎具有积极的治疗意义和临床应用价值。 Objective To investigate the clinical efficacy of early endoscopic treatment of acute pancreatitis (AP). Methods In the treatment group (37 cases), pancreaticobiliary imaging was performed in the early stage of AP in addition to conventional medical treatment. According to the results, endoscopic treatment including nipple sphincterotomy and / or nasobiliary drainage was performed. The control group (56 cases) only received general medical treatment. Results The pain relief time and the average hospitalization days in the treatment group were lower than those in the control group (P <0.05). In the treatment group, the cure rate was 97.3% (36/37) in the control group and 78.6% (44/56) in the control group. Conclusion Early endoscopic treatment of AP with minimal trauma to achieve satisfactory drainage effect of acute pancreatitis has a positive therapeutic value and clinical value.