论文部分内容阅读
目的:探讨上海市卢湾区社区女性乳腺癌发生的危险因素。方法:2008年12月至2009年2月,以问卷调查形式对社区女性进行普查,通过条件logistic回归分析,研究社区女性患乳腺癌的危险因素。结果:普查社区女性共计6 171名,年龄20～92岁,中位年龄58岁,其中乳腺癌病人91例。通过条件logistic回归分析显示,首次足月妊娠年龄(>35岁)、绝经后体重增加(>2.5 kg)、绝经年龄(>55岁)、乳腺癌家族史、卵巢癌家族史、体质量指数(BMI,≥25)等为社区女性患乳腺癌的危险因素,哺乳为保护因素;绝经前女性患乳腺癌的危险因素包括月经初潮年龄(<12岁)、首次足月妊娠年龄(>35岁)、乳腺癌家族史和BMI(≥30)等,生育史和哺乳为保护因素。结论:需进一步加强针对乳腺癌危险因素的一、二级预防。
Objective: To investigate the risk factors of breast cancer in community of Luwan District in Shanghai. Methods: From December 2008 to February 2009, the community women were surveyed by questionnaire survey. The risk factors of breast cancer in community women were studied by conditional logistic regression analysis. Results: A total of 6 171 women in the census community were aged 20 to 92 years with a median age of 58 years, of whom 91 were breast cancer patients. Logistic regression analysis showed that the first full-term gestational age (> 35 years), postmenopausal weight gain (> 2.5 kg), menopause (> 55 years), breast cancer family history, ovarian cancer family history, body mass index BMI, ≥25) were risk factors for breast cancer in community women and lactation was a protective factor. Risk factors for breast cancer in premenopausal women included menarche (<12 years old), first full-term gestational age (> 35 years) , Family history of breast cancer and BMI (≥30), fertility history and breastfeeding as a protective factor. Conclusion: It is necessary to further strengthen primary and secondary prevention against breast cancer risk factors.