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为评价国产司帕沙星片的临床疗效与安全性 ,采用洛美沙星片为对照 ,共治疗急性细菌性感染 70例 ,其中试验组与对照组各 35例。司帕沙星 2 0 0mgQD ,洛美沙星 30 0mgBid ,疗程 7～ 14日。结果显示 ,试验组和对照组的临床痊愈率均为 80 0 0 % ,有效率分别为 94 2 9%和 97 14% ,细菌清除率分别为 93 94%和 93 75 % ,不良反应发生率分别为 8 75 %和 5 71%。以上结果两组比较均无统计学差异 (P >0 0 5 )。本研究表明 ,国产司帕沙星片治疗急性细菌性感染安全、有效 ,且使用简便、日仅用药一次。
To evaluate the clinical efficacy and safety of domestic sparfloxacin tablets, Lomefloxacin tablets were used as control to treat 70 cases of acute bacterial infections, of which 35 cases in the test group and the control group. Sparfloxacin 200mgQD, lomefloxacin 30 0mgBid, treatment 7 to 14 days. The results showed that the clinical cure rate of the experimental group and the control group were 80 0 0%, the effective rates were 94 2 9% and 97 14%, the bacterial clearance rates were 93 94% and 93 75% respectively, the rates of adverse reactions were 8 75% and 5 71%. The above results were no significant difference between the two groups (P> 0.05). This study shows that domestic sparfloxacin tablets for the treatment of acute bacterial infections safe, effective, and easy to use, only once a day.