目的　评价甲亢伴周期性麻痹 1 31 I治疗的疗效。方法　 31例甲亢伴周期性麻痹的患者采取 1 31 I治疗 ,所有病例至少随访半年以上 ,按治疗的效果分为治愈、部分缓解、甲低、无效四组 ,统计各组的发生率 ,对其结果进行分析。结果　 31例患者治愈 2 2例 ,占 71 .0 % ;甲低 5例 ,占 1 6 .1 % ;无效 4例 ,占 1 2 .9%。结论　 1 31 I治疗甲亢伴周期性麻痹具有治愈率高、简单、安全等特点 ,能克服抗甲状腺药物或手术治疗的某些不足 ,治疗后有一定的甲低发生率。在 1 31 I治疗时 ,应尽可能多考虑可能影响 1 31 I治疗剂量制定的因素 ,减少甲低的发生率 Objective To evaluate the efficacy of hyperthyroidism with periodic paralysis.131I treatment. Methods 31 cases of hyperthyroidism with periodic paralysis were treated with 131 I, all cases were followed up for at least six months, according to the effect of treatment were divided into four groups were cured, partial remission, hypothyroidism, ineffective four groups, the incidence of each group, its Results were analyzed. Results 31 patients were cured 22 cases, accounting for 71.0%; hypothyroidism in 5 cases, accounting for 16.1%; 4 cases ineffective, accounting for 12.9%. Conclusion 1 31 I treatment of hyperthyroidism with periodic paralysis has a high cure rate, simple, safe and can overcome some shortcomings of antithyroid drugs or surgical treatment, after treatment there is a certain incidence of hypothyroidism. In the treatment of 131I, as much as possible should be considered factors that may affect the amount of 131I treatment to reduce the incidence of hypothyroidism