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目的:对比血液透析与腹膜透析治疗老年糖尿病终末期肾病(ESRD)的效果。方法:将56例ESRD患者随机分成观察组(28例)与对照组(28例)。观察组患者采取血液透析治疗,对照组患者采取腹膜透析治疗。观察两组治疗前后各项临床生化指标具体情况,同时对比两组患者透析治疗期间不良反应发生情况。结果:透析后两组血压均降低,但是对照组血压下降程度高于对照组(P<0.05);透析后两组肌酐、尿氮素均下降,但是观察组下降程度高于对照组(P<0.05);对照组透析后血红蛋白下降程度高于对照组(P<0.05);透析后两组血红丹巴均上升,组间无差异(P>0.05);透析前后两组患者血钾与血糖水平无显著差异(P>0.05);观察组透析治疗期间不良反应发生率为50.0%,观察组不良反应发生率为46.43%,差异不具有统计学意义(P>0.05)。结论:血液透析与腹膜透析都是治疗老年糖尿病终末期肾病的有效方法,同时两种治疗方法的并发症也都较多。
Objective: To compare the effects of hemodialysis and peritoneal dialysis on senile diabetic end-stage renal disease (ESRD). Methods: 56 ESRD patients were randomly divided into observation group (28 cases) and control group (28 cases). Patients in the observation group were treated with hemodialysis, while patients in the control group were treated with peritoneal dialysis. Before and after treatment, the clinical and biochemical indexes of the two groups were observed. The incidence of adverse reactions was compared between the two groups during the dialysis treatment. Results: After dialysis, the blood pressure of both groups decreased, but the decrease of blood pressure in the control group was higher than that of the control group (P <0.05). After dialysis, creatinine and urine nitrogen of both groups decreased, but decreased in the observation group (P < 0.05). After the dialysis, hemoglobin decreased in the control group was higher than that in the control group (P <0.05). After hemodialysis, hemodanba increased in both groups (P> 0.05); before and after dialysis, serum potassium and blood glucose (P> 0.05). The incidence of adverse reactions in observation group was 50.0% during dialysis treatment and 46.43% in observation group. The difference was not statistically significant (P> 0.05). Conclusion: Both hemodialysis and peritoneal dialysis are effective methods for the treatment of end-stage renal disease in elderly patients with diabetes, and there are more complications in both treatment methods.