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化疗、放疗、手术治疗单独或联合是目前治疗恶性肿瘤的主要手段。放疗、化疗引起的骨髓抑制,造成外周血白细胞减少,是常见和较严重的合并症[1]。临床上除了一般的支持治疗,控制感染,必要时输注粒细胞外,最主要的是应用重组人粒细胞集落刺激因子(rhG-CSF,如赛格力)和重组人粒细胞-巨噬细胞集落刺激因子(rhGM-CSF,如特尔立),缩短白细胞低下维持的时间,促使白细胞尽快恢复,使化疗或放疗顺利按计划进行[2,3]。
Chemotherapy, radiotherapy, surgical treatment alone or in combination is the main means of treatment of malignant tumors. Radiotherapy, chemotherapy-induced bone marrow suppression, resulting in peripheral leukopenia, is a common and more serious complications [1]. In addition to the general supportive treatment, infection control, if necessary, infusion of granulocytes, the most important is the application of recombinant human granulocyte colony-stimulating factor (rhG-CSF, such as SAGE) and recombinant human granulocyte-macrophage Colony-stimulating factor (rhGM-CSF, such as Tellabs), shorten the maintenance of leukopenia time to promote the rapid recovery of white blood cells, chemotherapy or radiotherapy smoothly according to plan [2,3].