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本文根据乙酰胆碱酯酶活性中心肽片段的结构,以丝氨酸为中心,辅以对水解乙酰胆碱有影响的氨基酸残基,合成了6个小肽类似物。其中间体皆通过元素分析和波谱分析证实,最终产物通过氨基酸组分分析证实。
According to the structure of acetylcholinesterase activity center peptide fragment, six small peptide analogues were synthesized with amino acid residues centered on serine and assisted by hydrolysis of acetylcholine. The intermediates were confirmed by elemental analysis and spectral analysis, and the final product was confirmed by amino acid composition analysis.