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目的 探讨蚌埠市五河县 1999年 1~ 4月份甲型肝炎发病升高原因及防治对策。方法 根据相关疫情资料结合统一调查表 (问卷 )收集的免疫史等甲肝发病信息资料 ,健康人群HAV -IgG抗体水平调查结果 ,进行流行病学回顾性分析。结果 1998年 10月~ 1999年 4月、1997年 10月~ 1998年 4月甲肝发病均以10岁以下散居儿童为主 ;男性明显高于女性。病例主要分布在水网密集地区和交通相对发达的地区 ;仅 5 .4 1% (34/ 6 2 9)及时隔离治疗 ,乡以下诊断的病例中仅 4 3.77% (130 / 2 97)是通过临床和特异性复合诊断 ;HAV-IgG抗体阳性率有随年龄增长而升高的趋势。结论 五河县甲肝爆发流行与水网密集、交通发达的地理特征引起的爆发和扩散 ,10以下儿童甲肝易感人群积累、传染源管理的失控、误诊等主观因素有关。建议防治中注重根据具体情况采取针对性措施 ,且考虑措施综合性。
Objective To investigate the causes and prevention and treatment of hepatitis A in Wuhe County, Bengbu from January to April in 1999. Methods The epidemiological retrospective analysis of HAV-IgG antibody levels in healthy population based on information of relevant epidemic situation and immunization history collected in the questionnaire (questionnaire) and other hepatitis A pathogens was conducted. Results From October 1998 to April 1999, from October 1997 to April 1998, the incidence of hepatitis A were mainly those of children under 10 years of age. The prevalence of hepatitis A was significantly higher in males than in females. The cases were mainly distributed in densely populated water areas and areas with relatively developed traffic. Only 5.41% (34/62 29) were treated with timely isolation. Only 3.77% (130/297) of the cases diagnosed below the township were confirmed by Clinical and specific composite diagnosis; HAV-IgG antibody positive rate with the increasing trend of age. Conclusions The outbreak of hepatitis A in Wuhe County is related to the outbreak and spread caused by the dense water network, the developed geographic features, the accumulation of susceptible people with hepatitis A in children below 10, the uncontrolled and misdiagnosis of infection source management. It is suggested that prevention and treatment should focus on taking specific measures according to specific situations and considering the comprehensiveness of measures.