应用氢化发生-原子荧光光谱法测定某品牌天王补心丹中汞的含量,分析对测定有影响的因素并优化实验条件,为该中成药的质量控制和用药安全性提供科学依据。采用硝酸-高氯酸敞开湿法消解样品。在最佳实验条件下,方法的检出限为0.0387μg/L,相对标准偏差均小于1.5%,加标回收率为106.0%—113.7%。方法简单、快速,重现性好。 Hydrogenation - atomic fluorescence spectrometry was used to determine the content of mercury in a certain brand of Buxus Tenan. Then the influencing factors were analyzed and the experimental conditions were optimized to provide a scientific basis for the quality control and drug safety of this proprietary Chinese medicine. Open samples were wet-digested with nitric acid-perchloric acid. Under the optimal experimental conditions, the detection limit was 0.0387 μg / L, the relative standard deviations were less than 1.5% and the recoveries were 106.0% -113.7%. The method is simple, fast and reproducible.