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1993年3月到1995年12月对本市三家医院的婴儿室进行定期院内感染监测。共采取标本1089份,分离出金黄色葡萄球菌198株,其中耐甲氧西林金黄色葡萄球菌(MRSA)112株(占56.5%)。对MRSA进行生物学鉴定、耐药谱测定及噬菌体分型(Ⅰ群最多占59.8%),所有MRSA对青霉素、氨苄青霉素、林可霉素耐药,对喹诺酮类药物敏感性较高但易出现耐药株,对万古霉素均敏感。另外对112株MRSA的院内分布进行了统计分析,提出了控制婴儿室MRSA院内感染发生的措施,认为合理使用抗生素、婴儿室用品的严格彻底消毒灭菌是其关键。
From March 1993 to December 1995, regular monitoring of nosocomial infection was performed in the infant rooms of three hospitals in the city. A total of 1089 specimens were taken and 198 strains of Staphylococcus aureus were isolated, of which 112 strains (56.5%) were resistant to methicillin-resistant Staphylococcus aureus (MRSA). MRSA biological identification, determination of drug resistance spectrum and phage typing (up to a group of 59.8%), all MRSA resistant to penicillin, ampicillin, lincomycin, quinolones sensitive Easily resistant strains, are sensitive to vancomycin. In addition, a statistical analysis of the distribution of 112 MRSA hospitals was made, and measures to control the occurrence of nosocomial infections in the infant room were put forward. It is considered that the rational use of antibiotics and strict disinfection of the infant room supplies is the key.