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目的探讨醒脑静注射液联合盐酸纳洛酮注射液治疗脑出血伴昏迷患者的临床疗效。方法选取2013年3月—2015年3月临汾市人民医院收治的脑出血伴昏迷患者78例,随机分为观察组与对照组,各39例。两组患者均予以基础治疗,对照组患者予以盐酸纳洛酮注射液治疗,观察组患者在对照组基础上加用醒脑静注射液治疗。观察两组患者临床疗效、治疗前后格拉斯哥昏迷评分和脑血肿量、昏迷时间。结果观察组患者总有效率高于对照组,差异有统计学意义(P<0.05);治疗前两组患者格拉斯哥昏迷评分、脑血肿量比较,差异无统计学意义(P>0.05);治疗后观察组患者格拉斯哥昏迷评分高于对照组,脑血肿量少于对照组,差异有统计学意义(P<0.05);观察组患者昏迷时间短于对照组,差异有统计学意义(P<0.05)。结论醒脑静注射液联合盐酸纳洛酮注射液治疗脑出血伴昏迷患者的临床疗效显著,可促进患者意识恢复,降低脑血肿量,缩短昏迷时间。
Objective To investigate the clinical effects of xingnaojing injection combined with naloxone hydrochloride injection in patients with cerebral hemorrhage and coma. Methods From March 2013 to March 2015, 78 patients with cerebral hemorrhage and coma admitted to Linfen People’s Hospital were randomly divided into observation group and control group, with 39 cases in each group. Two groups of patients were treated with basic treatment, patients in the control group were treated with naloxone hydrochloride injection, and patients in the observation group were treated with xingnaojing injection on the basis of the control group. The clinical curative effect of two groups was observed. The Glasgow coma score and cerebral hematoma volume and coma time before and after treatment were observed. Results The total effective rate in the observation group was higher than that in the control group (P <0.05). There was no significant difference in the Glasgow coma score and cerebral hematoma volume between the two groups before treatment (P> 0.05) The Glasgow coma score in the observation group was higher than that in the control group, and the amount of cerebral hematoma was less in the control group (P <0.05). The coma time in the observation group was shorter than that in the control group (P <0.05) . Conclusion Xingnaojing injection combined with naloxone hydrochloride injection in the treatment of patients with cerebral hemorrhage coma clinical efficacy significantly, can promote recovery of consciousness, reduce the volume of cerebral hematoma and shorten the coma time.