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目的分析老年患者药品不良反应的发生情况,为临床合理用药提供参考。方法调查我院2005年1月至2008年6月上报的老年患者药品不良反应报告,共313份,用Excel软件进行统计和分析。结果老年患者药品不良反应占43.6%,老年患者药品不良反应所累及的系统-器官主要为皮肤及其附件(30.7%)、神经系统(15.8%)、消化系统(14.2%),诱发老年患者药品不良反应的药物主要是抗菌药物和治疗心脑血管病的药物。结论老年患者药品不良反应的高发生率与多种因素有关,需要加强监测,保障其用药安全。
Objective To analyze the incidence of adverse drug reactions in elderly patients and provide reference for clinical rational drug use. Methods A total of 313 reports of adverse drug reactions in elders reported in our hospital from January 2005 to June 2008 were collected and statistically analyzed with Excel software. Results The adverse drug reactions in elderly patients accounted for 43.6%. The adverse reactions to drug adverse reactions in elderly patients included the skin and its appendages (30.7%), the nervous system (15.8%), the digestive system (14.2%), the drugs Adverse reactions to drugs mainly antibiotics and drugs for the treatment of cardiovascular and cerebrovascular diseases. Conclusion The high incidence of adverse drug reactions in elderly patients is related to many factors, which need to be strengthened to ensure the safety of medication.