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辐射诱发体细胞突变出现躯体效应,而诱发生殖细胞突变表现为遗传负荷增加。过去多用辐射流行病学调查来评价这种遗传效应。如:日本原子弹爆炸受害者的子代遗传病调查等。但是,由于人的生育周期长,调查人数有限,迄今尚不能明确辐射的遗传影响。动物生育周期虽然短,也需要饲养大批亲代动物,以满足足够分析的子代动物数的需要,耗费大量人力物力。生殖细胞染色体畸变研究,可以直接评价遗传危
Radiation-induced somatic mutations appear somatic effects, while inducing germ cell mutations showed increased genetic load. In the past, radiation epidemiological surveys were used to evaluate this genetic effect. Such as: Japan’s atomic bomb victims of genetic disease investigation. However, due to the length of human life and the limited number of investigations, the genetic impact of radiation has so far not been identified. Although the animal breeding cycle is short, a large number of parental animals need to be kept in order to meet the needs of analyzing enough numbers of offspring animals and consume a large amount of manpower and resources. Germ cell chromosome aberration study, you can directly evaluate the genetic risk