目的分析2005-2015年潍坊市新发现艾滋病病毒(HIV)感染者/艾滋病(AIDS)病例(简称HIV/AIDS病例)的晚发现情况。方法从中国艾滋病综合防治信息系统中,选择2005-2015年新发现的、现住地为潍坊市的HIV/AIDS病例,按照目前中国使用的晚发现定义标准,分析不同情况下的晚发现比例。结果潍坊市2005-2015年658例HIV/AIDS病例中,晚发现病例182例,占27.66%。从多年的晚发现率分析,晚发现率总体呈下降趋势(χ~2趋势=5.725,P<0.001)。HIV/AIDS病例中,女性、50~59岁年龄段、小学及以下文化、农民、输血/血制品传播、样本来源于临床检测的晚发现率,分别高达43.61%、48.48%、43.07%、42.62%、88.24%、47.93%。单因素和多因素Logistics分析结果显示,性别、年龄、文化程度、职业、传播途径和样本来源是HIV/AIDS病例晚发现的独立影响因素(P<0.05);多因素Logistics回归分析显示,晚发现风险女性病例是男性的1.71倍,40~49岁、50~59岁年龄段分别是20~29岁年龄段的1.72和1.69倍,小学及以下文化是大专及以上的1.61倍,农民是其他的2.43倍,输血/血制品传播是同性性传播的2.35倍,样本来源于临床检测者是无偿献血者的5.90倍。结论潍坊市样本来源于临床检测病例的晚发现较为严重,应进一步加强对女性、高年龄段、文化程度偏低、职业为农民等重点人群的艾滋病扩大检测力度。 Objective To analyze the late detection of newly discovered cases of HIV / AIDS (Were HIV / AIDS cases) in Weifang City from 2005 to 2015. Methods From HIV / AIDS cases newly discovered in China from 2005 to 2015 and now living in Weifang City from China AIDS Integrated Prevention and Control Information System, the proportion of late-found cases in different situations was analyzed according to the definition criteria of late-found use in China. Results Among 658 HIV / AIDS cases from 2005 to 2015 in Weifang City, 182 cases were found later, accounting for 27.66%. From many years of late detection rate analysis, the late detection rate generally showed a downward trend (χ ~ 2 trend = 5.725, P <0.001). In HIV / AIDS cases, the rates of women, ages 50-59, primary and below cultures, peasants, blood transfusions / blood products were all derived from clinical detection of late detection rates as high as 43.61%, 48.48%, 43.07%, 42.62 %, 88.24%, 47.93%. Univariate and multivariate Logistic analysis showed that sex, age, education level, occupation, route of transmission and sample source were independent influencing factors of late onset of HIV / AIDS (P <0.05). Multi-factor Logistic regression analysis showed that late discovery The risk of female cases is 1.71 times that of men, 40 to 49 years old, 50 to 59 age groups are 1.72 and 1.69 times of 20 to 29 age groups, primary and below culture is 1.61 times higher than college and above, farmers are other 2.43 times. The blood transfusion / blood product spread is 2.35 times that of the same sex, the samples come from the clinical test who are 5.90 times of the blood donors. Conclusion Weifang City samples come from late detection of clinical test cases is more serious, we should further strengthen the detection of AIDS in women, high age groups, low education level, occupational as peasants and other key populations.